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人体深部和皮下黏液囊的透明质酸含量

Hyaluronic acid content of deep and subcutaneous bursae of man.

作者信息

Canoso J J, Stack M T, Brandt K D

出版信息

Ann Rheum Dis. 1983 Apr;42(2):171-5. doi: 10.1136/ard.42.2.171.

DOI:10.1136/ard.42.2.171
PMID:6847262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001094/
Abstract

To provide a comparison of the contents of subcutaneous and deep bursae we dissected these structures from unfixed cadavers without apparent joint disease. No free fluid was found within any olecranon or prepatellar bursae (examples of subcutaneous bursae), while viscous fluid was invariably present in the (deep) retrocalcaneal bursae. The hyaluronic acid content of the washings of 5 rectrocalcaneal bursae ranged from 142 to 591 nmol hexosamine (mean = 281 nmol hexosamine). In contrast, the hyaluronic acid content of 4 olecranon bursae was much lower (range 35-72 nmol, mean 53 nmol hexosamine), and hyaluronate was not detected in washings from either of 2 prepatellar bursae. The greater hyaluronate content of the retrocalcaneal bursae did not appear to be due to a greater surface area, since on the basis of calculations made from plaster casts the surface areas of the olecranon and prepatellar bursae were approximately 3 times and 2 times, respectively, greater than that of the retrocalcaneal bursae. The data suggest that, although hyaluronic acid may lubricate deep bursae, other factors may be more important in reducing friction within superficial bursae.

摘要

为了比较皮下滑囊和深部滑囊的内容物,我们从无明显关节疾病的未固定尸体上解剖了这些结构。在任何鹰嘴或髌前滑囊(皮下滑囊的例子)中均未发现游离液体,而在(深部)跟腱后滑囊中总是存在粘性液体。5个跟腱后滑囊冲洗液中的透明质酸含量在142至591nmol己糖胺之间(平均=281nmol己糖胺)。相比之下,4个鹰嘴滑囊的透明质酸含量要低得多(范围为35 - 72nmol,平均53nmol己糖胺),并且在2个髌前滑囊的冲洗液中均未检测到透明质酸盐。跟腱后滑囊中较高的透明质酸盐含量似乎并非由于表面积更大,因为根据石膏模型计算,鹰嘴滑囊和髌前滑囊的表面积分别约为跟腱后滑囊表面积的3倍和2倍。数据表明,尽管透明质酸可能润滑深部滑囊,但其他因素在减少浅表滑囊内的摩擦方面可能更为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592f/1001094/7e65f86ea1c5/annrheumd00116-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592f/1001094/349b825724ac/annrheumd00116-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592f/1001094/7e65f86ea1c5/annrheumd00116-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592f/1001094/349b825724ac/annrheumd00116-0068-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592f/1001094/7e65f86ea1c5/annrheumd00116-0069-a.jpg

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