Methaphenilene, an analogue of the antihistaminic methapyrilene, is a "peroxisome proliferator".

作者信息

Reznik-Schüller H M, Lijinsky W

出版信息

Arch Toxicol. 1983 Feb;52(2):165-6. doi: 10.1007/BF00354776.

DOI:10.1007/BF00354776

PMID:6847382

Abstract

摘要

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引用本文的文献

Carcinogenicity studies of some analogs of the carcinogen methapyrilene in F344 rats.

J Cancer Res Clin Oncol. 1986;112(1):57-60. doi: 10.1007/BF00394940.

本文引用的文献

Liver tumors induced in rats by oral administration of the antihistaminic methapyrilene hydrochloride.

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Morphology of early changes in liver carcinogenesis induced by methapyrilene.

Arch Toxicol. 1981 Nov;49(1):79-83. doi: 10.1007/BF00352075.

Induction of hamster hepatic peroxisomal beta-oxidation and peroxisome proliferation-associated 80000 mol. wt. polypeptide by hypolipidemic drugs.

Hum Toxicol. 1982 Mar;1(2):135-47. doi: 10.1177/096032718200100205.

Hepatic peroxisome proliferation: induction by two novel compounds structurally unrelated to clofibrate.

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