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[不同外周神经节神经细胞的信息分析及其分化关键期]

[Information analysis of neurocytes of various peripheral ganglia, and critical periods of their differentiation].

作者信息

Sluka B A

出版信息

Arkh Anat Gistol Embriol. 1983 Feb;84(2):16-22.

PMID:6847386
Abstract

Calculation of the informatory parameters of entropy and redundancy performed, taking as a base nuclear-cytoplasmic relations of neurocytes in the inferior ganglion of the vagus nerve, in the superior ganglion and in the interorganic ganglia of the respiratory tube, demonstrated certain interconnection of the integral characteristics obtained with some stages of the neuronal morphological differentiation. Periods of an abrupt reduction in the redundant information up to the minimal values which goes in parallel with an increasing entropy on the 2d-4th months of embryogenesis (taking into account heterochronia in the development of various ganglia) are considered as some critical periods in the neuron development when it passes to the stage of growth (the first critical period) and to the stage of maturation (the second critical period). Their existence is regarded in connection with the hierarchical joining of the vascular and neural trophic types of the vegetative ganglia. A supposition is made on a dependence of the specific neuronal differentiation on the epigenetic factors of morphogenesis.

摘要

以迷走神经下神经节、上神经节以及呼吸管器官间神经节中神经细胞的核质关系为基础,对熵和冗余的信息参数进行计算,结果表明所获得的积分特征与神经元形态分化的某些阶段存在一定的相互联系。在胚胎发育的第2 - 4个月(考虑到不同神经节发育的异时性),冗余信息急剧减少至最小值,同时熵增加,这一时期被视为神经元发育过程中的一些关键时期,此时神经元进入生长阶段(第一个关键时期)和成熟阶段(第二个关键时期)。它们的存在与植物性神经节的血管和神经营养类型的分层连接有关。有人推测特定的神经元分化依赖于形态发生的表观遗传因素。

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