Zubov N A, Zubkov V G
Arkh Patol. 1983;45(1):34-8.
Postmortem microscopic examinations and morphometry of the tissue components of the major duodenal papilla in 90 residents of the Tobolsk district who had long time suffered from opisthorchiasis revealed three variants of chronic proliferative papillitis: adenomatous, adenofibroplastic, and sclerosing. They reflect the successive stages of the inflammatory and immunologic reactions of the patients to long-term parasitising of opisthorchiases. Hyperplastic and inflammatory-sclerosing processes in the wall of the papilla ampoule are the main factor in the pathogenesis of diffuse cylindrical cholangiectasia frequently observed in chronic opisthorchiasis.
对90名长期患有后睾吸虫病的托博尔斯克地区居民的十二指肠大乳头组织成分进行尸检显微镜检查和形态测量，发现了慢性增殖性乳头炎的三种变体：腺瘤样、腺纤维增生性和硬化性。它们反映了患者对后睾吸虫长期寄生的炎症和免疫反应的连续阶段。乳头壶腹壁的增生和炎性硬化过程是慢性后睾吸虫病中常见的弥漫性圆柱状胆管扩张症发病机制的主要因素。
