Wilder W H, Harner S G, Banks P M
Arch Otolaryngol. 1983 May;109(5):310-2. doi: 10.1001/archotol.1983.00800190032008.
The records of 37 patients with lymphoma of the nose and paranasal sinuses in an 18-year period were studied. The symptoms were divided into three categories: (1) local symptoms: obstruction, bleeding, and rhinorrhea; (2) symptoms of invasion of adjacent structures: facial pain and ear fullness; and (3) systemic symptoms: fever, weight loss, and nocturnal sweating. The presence of an intranasal mass was the most common physical finding. Conventional tomography and computed tomography were helpful for diagnosis. Abnormalities were usually disclosed on biopsy specimens from the nose or mouth. As a rule, several sites in the nose and sinuses were involved. An early diagnosis of sinonasal lymphoma and other malignant neoplasms generally allows effective treatment; therefore, the otorhinolaryngologist should be alert for such disease and, if the clinical picture warrants, should add tomography to the diagnostic workup.
对18年间37例鼻及鼻窦淋巴瘤患者的记录进行了研究。症状分为三类：(1)局部症状：鼻塞、出血和流涕；(2)邻近结构受侵症状：面部疼痛和耳部闷胀感；(3)全身症状：发热、体重减轻和盗汗。鼻内肿物是最常见的体格检查发现。传统体层摄影术和计算机体层摄影术有助于诊断。通常在取自鼻或口的活检标本上发现异常。通常，鼻和鼻窦的几个部位会受累。鼻窦淋巴瘤和其他恶性肿瘤的早期诊断一般可实现有效治疗；因此，耳鼻喉科医生应警惕此类疾病，并且如果临床表现需要，应在诊断检查中增加体层摄影术。
