细胞色素P-450侧链裂解酶诱导氢过氧甾醇-二醇转化过程中瞬态物种形成的光谱证据。
Spectroscopic evidence for the formation of a transient species during cytochrome P-450scc induced hydroperoxysterol-glycol conversions.
作者信息
Larroque C, van Lier J E
出版信息
Biochem Biophys Res Commun. 1983 Apr 29;112(2):655-62. doi: 10.1016/0006-291x(83)91513-9.
PMID:6847670
Abstract
Spectroscopic analysis of the interaction of the epimeric 20-hydroperoxy derivatives of cholesterol with bovine adrenocortical cytochrome P-450scc preparations suggested the formation of a transient species. The intermediate was detected at 4 degrees C and characterized by a minimum at 412 nm in the difference spectrum.
摘要
胆固醇差向异构20-氢过氧化物衍生物与牛肾上腺皮质细胞色素P-450scc制剂相互作用的光谱分析表明形成了一种瞬态物质。该中间体在4℃下被检测到，其特征在于差示光谱中在412nm处有一个最小值。
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