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Specificity of systems mediating transport of adenosine, 9-beta-d-arabinofuranosyl-2-fluoroadenine, and other purine nucleoside analogues in L1210 cells.

作者信息

Sirotnak F M, Chello P L, Dorick D M, Montgomery J A

出版信息

Cancer Res. 1983 Jan;43(1):104-9.

PMID:6847758
Abstract
摘要

相似文献

1
Specificity of systems mediating transport of adenosine, 9-beta-d-arabinofuranosyl-2-fluoroadenine, and other purine nucleoside analogues in L1210 cells.
Cancer Res. 1983 Jan;43(1):104-9.
2
Initial rate kinetics and evidence for duality of mediated transport of adenosine, related purine nucleosides, and nucleoside analogues in L1210 cells.L1210细胞中腺苷、相关嘌呤核苷及核苷类似物介导转运的初始速率动力学及双重性证据
Cancer Res. 1983 Jan;43(1):97-103.
3
Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.基于与肿瘤细胞相比，增殖性肠上皮细胞中9-β-D-阿拉伯呋喃糖基-2-氟腺嘌呤的转运和磷酸化能力较低，提出其对小鼠白血病具有治疗选择性的机制。
Cancer Res. 1987 Feb 1;47(3):700-6.
4
Comparison of the actions of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine on target enzymes from mouse tumor cells.9-β-D-阿拉伯呋喃糖基-2-氟腺嘌呤与9-β-D-阿拉伯呋喃糖基腺嘌呤对小鼠肿瘤细胞靶酶作用的比较。
Cancer Res. 1982 Jun;42(6):2260-4.
5
Metabolism and chemotherapeutic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase.9-β-D-阿拉伯呋喃糖基-2-氟腺嘌呤对小鼠白血病L1210的代谢及化疗活性及其经脱氧胞苷激酶磷酸化的证据
Cancer Res. 1980 Oct;40(10):3610-5.
6
Substrate specificity, kinetics, and stoichiometry of sodium-dependent adenosine transport in L1210/AM mouse leukemia cells.L1210/AM小鼠白血病细胞中钠依赖性腺苷转运的底物特异性、动力学和化学计量学
J Biol Chem. 1991 Apr 5;266(10):6312-7.
7
Phosphorolytic cleavage of 2-fluoroadenine from 9-beta-D-arabinofuranosyl-2-fluoroadenine by Escherichia coli. A pathway for 2-fluoro-ATP production.大肠杆菌对9-β-D-阿拉伯呋喃糖基-2-氟腺嘌呤进行磷酸解裂产生2-氟腺嘌呤。这是一条生成2-氟-ATP的途径。
Biochem Pharmacol. 1987 Sep 15;36(18):2945-50. doi: 10.1016/0006-2952(87)90207-3.
8
Synergistic inhibition of leukemia L1210 cell growth in vitro by combinations of 2-fluoroadenine nucleosides and hydroxyurea or 2,3-dihydro-1H-pyrazole[2,3-a]imidazole.2-氟腺嘌呤核苷与羟基脲或2,3-二氢-1H-吡唑并[2,3-a]咪唑联合使用对白血病L1210细胞体外生长的协同抑制作用
Cancer Res. 1984 Aug;44(8):3286-90.
9
Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes.通过在非洲爪蟾卵母细胞中表达的大鼠空肠重组嘌呤和嘧啶选择性钠/核苷共转运体转运腺苷。
Mol Pharmacol. 1996 Dec;50(6):1529-35.
10
Biologic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine, a metabolically stable analog of 9-beta-D-arabinofuranosyladenine.9-β-D-阿拉伯呋喃糖基-2-氟腺嘌呤（9-β-D-阿拉伯呋喃糖基腺嘌呤的代谢稳定类似物）的生物活性。
Biochem Pharmacol. 1977 Nov 15;26(22):2193-6. doi: 10.1016/0006-2952(77)90275-1.

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The pentostatin plus cyclophosphamide nonmyeloablative regimen induces durable host T cell functional deficits and prevents murine marrow allograft rejection.喷司他丁联合环磷酰胺非清髓方案诱导持久的宿主 T 细胞功能缺陷并防止鼠骨髓移植物排斥。
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Fludarabine phosphate. A new anticancer drug with significant activity in patients with chronic lymphocytic leukemia and in patients with lymphoma.
磷酸氟达拉滨。一种对慢性淋巴细胞白血病患者和淋巴瘤患者具有显著活性的新型抗癌药物。
Invest New Drugs. 1994;12(2):75-92. doi: 10.1007/BF00874436.
4
Membrane transport and the antineoplastic action of nucleoside analogues.膜转运与核苷类似物的抗肿瘤作用
Cancer Metastasis Rev. 1987;6(4):459-80. doi: 10.1007/BF00047462.
5
Inhibition of fludarabine metabolism by arabinosylcytosine during therapy.治疗期间阿糖胞苷对氟达拉滨代谢的抑制作用。
Cancer Chemother Pharmacol. 1992;31(3):193-9. doi: 10.1007/BF00685547.
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Protection against fludarabine neurotoxicity in leukemic mice by the nucleoside transport inhibitor nitrobenzylthioinosine.核苷转运抑制剂硝基苄硫肌对白血病小鼠氟达拉滨神经毒性的保护作用
Cancer Chemother Pharmacol. 1992;31(1):71-5. doi: 10.1007/BF00695997.