Effer S B, Saigal S, Rand C, Hunter D J, Stoskopf B, Harper A C, Nimrod C, Milner R
Am J Obstet Gynecol. 1983 Jan 15;145(2):123-8. doi: 10.1016/0002-9378(83)90477-5.
The perinatal mortality rate among very low-birth weight infants has been decreased by 20% during the last 4 years of the 1973 to 1980 period here reported. The concurrent increase in the cesarean section rate from 11.9% to 49.1% during the same time frames has been assumed to be responsible for the improved outcome. The changes were most marked in the extremely low-birth weight group (less than 1,000 gm). The survival rates and cesarean section rates were examined among infants of similar birth weight and gestational age in the vertex presentation, in the same time frames. A similar or greater reduction in mortality rate (from 85% to 45%) was noted in the very low-birth weight vertex infants, whereas the cesarean section rate remained minimally and not significantly increased (14.2% to 22.2%). The interpretation of this finding is by no means clear but must include the hypothesis that the increased cesarean section rate may be incidental and in no way related to the improved outcome. The most statistically significant determinants of outcome remain birth weight and gestational age strata, with no significant difference in outcomes when the extremely low-birth weight group is analyzed separately from the entire very low-birth weight group. As yet unidentified perinatal care practices, other than cesarean section, may be more likely to affect outcome in this high-risk group.
在本文所报告的1973年至1980年期间的最后4年里,极低出生体重儿的围产期死亡率下降了20%。同期剖宫产率从11.9%上升至49.1%,人们认为这一上升是导致结局改善的原因。这些变化在超低出生体重组(低于1000克)最为明显。在同一时间段内,对胎位为头先露、出生体重和胎龄相似的婴儿的存活率和剖宫产率进行了检查。在极低出生体重的头先露婴儿中,死亡率有相似或更大程度的降低(从85%降至45%),而剖宫产率仅略有上升且无显著增加(从14.2%升至22.2%)。这一发现的解读绝非清晰明了,但必须考虑到这样一种假设,即剖宫产率的上升可能是偶然的,与结局的改善毫无关系。对结局最具统计学意义的决定因素仍然是出生体重和胎龄分层,当将超低出生体重组与整个极低出生体重组分开分析时,结局并无显著差异。除剖宫产外,尚未明确的围产期护理措施可能更有可能影响这一高危群体的结局。