Stahl S M, Kasser I S
Ann Emerg Med. 1983 Jan;12(1):28-31. doi: 10.1016/s0196-0644(83)80130-9.
A patient who ingested 1.5 g pentazocine developed status epilepticus, coma, respiratory depression, acidosis, profound hypotension, and ventricular arrhythmias. Although this patient survived after institution of general supportive measures, she did not respond to usual doses of naloxone. We describe the clinical symptoms and course of recovery of a patient with pentazocine overdose. Our case suggests that pentazocine overdose may require higher doses of naloxone (5 to 20 mg) than are customarily used for narcotic overdoses.
一名摄入1.5克喷他佐辛的患者出现了癫痫持续状态、昏迷、呼吸抑制、酸中毒、严重低血压和室性心律失常。尽管该患者在采取一般支持措施后存活下来，但对常规剂量的纳洛酮无反应。我们描述了一名喷他佐辛过量患者的临床症状和恢复过程。我们的病例表明，喷他佐辛过量可能需要比通常用于麻醉剂过量的剂量更高的纳洛酮剂量（5至20毫克）。
