Bouras N, Standish-Barry H, Bridges P K, Al-Yassiri M
Br J Clin Pharmacol. 1983 Apr;15(4):493-4. doi: 10.1111/j.1365-2125.1983.tb01536.x.
A special clinic was set up in an attempt to overcome the problem of accumulating a sufficient number of depressed patients for inclusion in clinical trials. Only 21 patients of the 81 patients referred during 1 year fulfilled the criteria for inclusion in the trials. The function of the special clinic did not prove successful as a similar proportion of depressed patients was found in a comparison group referred to the district psychiatric outpatient clinic.
设立了一个特殊诊所,试图解决招募足够数量的抑郁症患者纳入临床试验的问题。在1年中转诊的81名患者中,只有21名符合纳入试验的标准。事实证明,这个特殊诊所的作用并不成功,因为在转诊至地区精神科门诊的对照组中,发现抑郁症患者的比例与之相似。