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与抗抑郁药临床研究相关的一些问题和困难。

Some of the problems and difficulties associated with clinical studies of antidepressant agents.

作者信息

Jenner F A

出版信息

Br J Clin Pharmacol. 1977;4Suppl 2(Suppl 2):199S-207S. doi: 10.1111/j.1365-2125.1977.tb05753.x.

Abstract

The fact that the classification of psychopharmacological agents depends on clinical studies is emphasized. The difficulties in defining homogeneous groups of depressed patients are emphasized. Some contradictions in the literature are considered. Caution in interpreting the literature on antidepressant agents is recommended.

摘要

强调了精神药理学药物的分类取决于临床研究这一事实。强调了界定抑郁症患者同质群体的困难。考虑了文献中的一些矛盾之处。建议在解读抗抑郁药文献时要谨慎。

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本文引用的文献

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The symptomatic relief of anxiety with meprobamate, phenobarbital and placebo.
Am J Psychiatry. 1959 Apr;115(10):905-10. doi: 10.1176/ajp.115.10.905.
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Development of a rating scale for primary depressive illness.原发性抑郁症评定量表的编制。
Br J Soc Clin Psychol. 1967 Dec;6(4):278-96. doi: 10.1111/j.2044-8260.1967.tb00530.x.
9
Depressive pattern, social background, and hospitalization.抑郁模式、社会背景与住院治疗
J Nerv Ment Dis. 1970 Jun;150(6):466-78. doi: 10.1097/00005053-197006000-00006.

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