Cairns T, Siegmund E G, Stamp J J, Skelly J P
Biomed Mass Spectrom. 1983 Mar;10(3):203-8. doi: 10.1002/bms.1200100317.
Chemical ionization mass spectra of dexamethasone and betamethasone have been obtained via liquid chromatography mass spectrometry using a moving belt interface. These results have confirmed a concentration-dependent competition between thermal degradation and vaporization. Caution should be exercised when dealing with molecules subject to thermal instability since sample introduction via the mechanical transport system does not guarantee evaporation without thermal decomposition.
通过使用移动带接口的液相色谱质谱联用仪获得了地塞米松和倍他米松的化学电离质谱。这些结果证实了热降解和汽化之间存在浓度依赖性竞争。在处理受热不稳定的分子时应谨慎，因为通过机械传输系统引入样品并不能保证在不发生热分解的情况下蒸发。
