Berger R, Bernheim A, Mitelman F, Rydholm A
Cancer Genet Cytogenet. 1983 Jun;9(2):145-50. doi: 10.1016/0165-4608(83)90035-3.
The pattern of heteromorphisms in the C-band-positive constitutive heterochromatin of human chromosomes No. 1, 9, and 16 was studied in peripheral lymphocytes of 45 patients with soft tissue sarcomas and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and incidence of inversions. No consistent differences were found in these parameters between controls and sarcoma patients.
在45例软组织肉瘤患者和78例对照个体的外周血淋巴细胞中,研究了1号、9号和16号人类染色体C带阳性组成型异染色质的异态性模式。所分析的异染色质区域参数包括相对大小、同源染色体内的对称-不对称性以及倒位发生率。在对照和肉瘤患者之间,这些参数未发现一致的差异。