Pence D B, Stone J E
Vet Pathol. 1978 May;15(3):322-31. doi: 10.1177/030098587801500306.
Aortic lesions pathognomonic for Spirocerca lupi were found in 123 of 150 (82%) coyotes, Canis latrans, 23 of 66 (35%) bobcats, Felis rufus, one of five gray foxes, Urocyon cinereoargenteus and one of two red foxes, Vulpes vulpes, examined in West Texas. Adult nematodes in the esophagus were recovered from 11 of 150 (7%) coyotes. In the aorta there was initially an acute inflammatory response followed by an eosinophilic granuloma surrounding larval nematodes. The principal lesions was scarring of the aorta with replacement of elastic tissue with collagen. There was blockage of the intervertebral arteries, pitting and formation of granulomatous nodules on the intimal surface and scarring with diverticula and anuerysms in affected animals. The response to adult nematodes in the esophagus was usually a small eosinophilic granuloma surrounding the worms. There was no evidence of esophageal sarcoma or spondylosis deformans of thoracic vertebrae as reported in the dog.
在西德克萨斯检查的150只郊狼（犬属）中有123只（82%）、66只山猫（短尾猫属）中有23只（35%）、5只灰狐（灰狐属）中有1只以及2只赤狐（赤狐属）中有1只发现了狼旋尾线虫特有的主动脉病变。从150只郊狼中的11只（7%）体内回收了位于食管的成年线虫。在主动脉中，最初会出现急性炎症反应，随后是围绕幼虫线虫的嗜酸性肉芽肿。主要病变是主动脉瘢痕形成，弹性组织被胶原组织取代。在受影响的动物中，椎间动脉堵塞，内膜表面出现凹痕和肉芽肿性结节形成，以及伴有憩室和动脉瘤的瘢痕形成。对食管中成年线虫的反应通常是围绕虫体的小嗜酸性肉芽肿。没有证据表明存在如犬类中所报道的食管肉瘤或胸椎脊柱关节病。
