复发性流产的细胞遗传学

Cytogenetics of recurrent abortions.

作者信息

Lyberatou-Moraitou E, Grigori-Kostaraki P, Retzepopoulou Z, Kosmaidou-Aravidou Z

出版信息

Clin Genet. 1983 Apr;23(4):294-7. doi: 10.1111/j.1399-0004.1983.tb01879.x.

DOI:10.1111/j.1399-0004.1983.tb01879.x

Abstract

G-banded chromosome complements were analysed from both partners of 150 couples who had had two or more spontaneous abortions. Two women and four men were found to be balanced translocation carriers, as follows: 46,XX,t(2;10), 46,XX,t(6;11), 46,XY,t(6;10), 45,XY,t(13;14), 45,XY,t(13;14), 45,XY,t(14;21). Another woman had an abnormal karotype 46,XX/47,XXX and a man had a pericentric inversion of chromosome 1; six other men and two women had pericentric inversions of chromosome 9.

摘要

对150对有两次或更多次自然流产经历的夫妇双方的G显带染色体组型进行了分析。发现两名女性和四名男性为平衡易位携带者，具体如下：46,XX,t(2;10)、46,XX,t(6;11)、46,XY,t(6;10)、45,XY,t(13;14)、45,XY,t(13;14)、45,XY,t(14;21)。另一名女性有异常核型46,XX/47,XXX，一名男性有1号染色体的臂间倒位；另外六名男性和两名女性有9号染色体的臂间倒位。