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癫痫发作与平民头部损伤。

Seizures and civilian head injuries.

作者信息

Desai B T, Whitman S, Coonley-Hoganson R, Coleman T E, Gabriel G, Dell J

出版信息

Epilepsia. 1983 Jun;24(3):289-96. doi: 10.1111/j.1528-1157.1983.tb04892.x.

DOI:10.1111/j.1528-1157.1983.tb04892.x
PMID:6851962
Abstract

Although several studies have reported on the risk of "early seizures" (seizures occurring within 7 days following a head injury), the reported proportions of patients experiencing these seizures vary from 1.4 to 15%. This wide divergence may be due to problems with methodology such as case selection and definitions of head injury and early seizures. In a series of 702 patients admitted with a head injury to Cook County Hospital (CCH), Chicago, Illinois, 29 (4.1%) had early seizures. This proportion is twice as high as one previously reported in a comparable series. This may reflect an actual difference between the two series or a case selection bias serving to elevate the proportion of patients with early seizures at CCH.

摘要

尽管有多项研究报告了“早期癫痫发作”(头部受伤后7天内发生的癫痫发作)的风险,但报告的经历这些癫痫发作的患者比例从1.4%到15%不等。这种巨大差异可能是由于诸如病例选择以及头部损伤和早期癫痫发作的定义等方法学问题所致。在伊利诺伊州芝加哥市库克县医院(CCH)收治的702例头部受伤患者中,有29例(4.1%)发生了早期癫痫发作。这一比例是之前在类似病例系列中报告的比例的两倍。这可能反映了两个系列之间的实际差异,或者是一种病例选择偏倚,导致CCH早期癫痫发作患者的比例升高。

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引用本文的文献

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J Korean Neurosurg Soc. 2017 Sep;60(5):584-590. doi: 10.3340/jkns.2016.0707.008. Epub 2017 Aug 30.
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Inflammation in epileptogenesis after traumatic brain injury.创伤性脑损伤后癫痫发生过程中的炎症反应。
J Neuroinflammation. 2017 Jan 13;14(1):10. doi: 10.1186/s12974-016-0786-1.
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Post-traumatic epilepsy: an overview.创伤后癫痫:综述
Therapy. 2010 Sep;7(5):527-531. doi: 10.2217/THY.10.57.
4
Subclinical early posttraumatic seizures detected by continuous EEG monitoring in a consecutive pediatric cohort.连续 EEG 监测发现连续儿科队列中的亚临床早期创伤后癫痫发作。
Epilepsia. 2013 Oct;54(10):1780-8. doi: 10.1111/epi.12369. Epub 2013 Sep 13.
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Blood-brain barrier breakdown following traumatic brain injury: a possible role in posttraumatic epilepsy.创伤性脑损伤后血脑屏障破坏:在创伤后癫痫中可能发挥的作用
Cardiovasc Psychiatry Neurol. 2011;2011:765923. doi: 10.1155/2011/765923. Epub 2011 Feb 22.
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Posttraumatic epilepsy: a major problem in desperate need of major advances.外伤性癫痫:亟待重大突破的重大问题。
Epilepsy Curr. 2006 Jan-Feb;6(1):1-5. doi: 10.1111/j.1535-7511.2005.00083.x.
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Post-traumatic early epilepsy in pediatric age group with emphasis on influential factors.
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Early seizures after moderate closed head injury.中度闭合性颅脑损伤后的早期癫痫发作。
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Relative risk of deterioration after mild closed head injury.轻度闭合性颅脑损伤后病情恶化的相对风险。
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