Aust L, Bruckner J, Levachev M M, Noak R, Pokrovskiĭ A A
Vopr Pitan. 1978 Jul-Aug(4):18-23.
The fatty acids middle-chain triglycerides (FAMCT) may be considered as a possible component of alimentary mixtures intended to lower the energy-giving efficiency of the nutritional ration. They do not join the tissue lipids, whereas their reconstruction into long-chain fatty acids requires an additional expenditure of energy. These facts were confirmed by the results obtained in tests on rats. Feeding of growing rats for 5 weeks on a ration containing 12 per cent of the FAMCT on condition of a sufficient administration of polyunsaturated fatty acids (PUFA) through addition of sunflower seed oil led to a significant fall of the body mass gain by comparison with that in rats receiving a ration whose main source of fat was lard. An increased tryglycerides synthesis in the liver was not accompanied by their accumulation in the organ. The triglycerides level in the serum was up. An analysis of the fatty acids composition in the epididymitic fatty tissue, plasma and erythrocytes confirmed that the FAMCT C2-fragments developing during metabolization are used up chiefly in lipogenesis, one of the basic products of which is palmitic acid. The metabolization of FAMC with sufficient PUFA proportion in the ration does not derange the plastic function of fat in the organism, i.e, securing biosynthesis of lipid components of the membranes.
中链甘油三酯脂肪酸（FAMCT）可被视为旨在降低营养配给供能效率的营养混合物的一种可能成分。它们不会融入组织脂质，而将其重新转化为长链脂肪酸需要额外消耗能量。这些事实在对大鼠的试验中得到了证实。在通过添加葵花籽油充分给予多不饱和脂肪酸（PUFA）的条件下，用含有12% FAMCT的饲料喂养生长中的大鼠5周，与接受以猪油为主要脂肪来源的饲料的大鼠相比，体重增加显著下降。肝脏中甘油三酯合成增加，但并未伴随其在器官中的积累。血清中甘油三酯水平升高。对附睾脂肪组织、血浆和红细胞中脂肪酸组成的分析证实，代谢过程中产生的FAMCT C2片段主要用于脂肪生成，其主要产物之一是棕榈酸。在饲料中PUFA比例充足的情况下，FAMC的代谢不会扰乱机体中脂肪的塑形功能，即确保膜脂质成分的生物合成。
