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母亲在孕期服用丙硫氧嘧啶的儿童的智力发育

Intellectual development in children whose mothers received propylthiouracil during pregnancy.

作者信息

Burrow G N, Klatskin E H, Genel M

出版信息

Yale J Biol Med. 1978 Mar-Apr;51(2):151-6.

Abstract

Standard intelligence tests were administered to twenty-eight children who had been exposed to PTU in utero and thirty-two non-exposed siblings. There was no significant difference in results between the two groups. The present study suggests that with careful attention, pregnant women with thyrotoxicosis can be treated with propylthiouracil without interfering with subsequent intellectual development in the offspring.

摘要

对28名在子宫内接触过丙硫氧嘧啶(PTU)的儿童和32名未接触过的同胞兄弟姐妹进行了标准智力测试。两组结果之间没有显著差异。本研究表明,只要给予密切关注,患有甲状腺毒症的孕妇可以用丙硫氧嘧啶进行治疗,而不会干扰后代随后的智力发育。

相似文献

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Intellectual capacity of subjects exposed to methimazole or propylthiouracil in utero.
Eur J Pediatr. 1992 Aug;151(8):558-9. doi: 10.1007/BF01957719.
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Children exposed in utero to propylthiouracil. Subsequent intellectual and physical development.
Am J Dis Child. 1968 Aug;116(2):161-5. doi: 10.1001/archpedi.1968.02100020163007.
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Thyrotoxicosis and pregnancy.甲状腺毒症与妊娠
Trans Am Clin Climatol Assoc. 1974;85:18-23.

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