出生后给予过量维生素A的大鼠髓鞘形成受损。
Impaired Myelination in rats given excess vitamin A postnatally.
作者信息
Joshi H C, Shukla R R, Srivastava N, Misra U K
出版信息
Int J Vitam Nutr Res. 1983;53(1):19-22.
PMID:6853056
Abstract
The effect of postnatal administration of 1000 I.U. of Vitamin A on 4th, 6th, 8th, and 10th day of age to rat pups has been studied on brain myelin lipid and sulphatide synthesis from Na235SO4. Administration of vitamin A reduced brain weight, free cholesterol, phosphatidal ethanolamine and the synthesis of myelin sulphatides from Na235SO4.
摘要
研究了在出生后第4、6、8和10天给幼鼠腹腔注射1000国际单位维生素A对脑髓磷脂脂质和由Na235SO4合成硫脂的影响。维生素A的注射降低了脑重量、游离胆固醇、磷脂酰乙醇胺以及由Na235SO4合成髓磷脂硫脂的量。
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