Heim J, Massart C
J Gynecol Obstet Biol Reprod (Paris). 1983;12(1):27-30.
In 19 patients with unexplained hirsutism without virilisation, a check-up includes delta 4- androstenedione (A), testosterone, DHEA-S. A appears like the best hyperandrogenemia parameter. Nevertheless 5 patients among this group have normal values of all these hormones. A mild congenital adrenal hyperplasia by 21 hydroxylase deficiency is revealed by abnormal response of 17 -OH-progesterone in the cosyntropin test. Our normal value of delta-OHP is, according to Gutai, method, 1.58 +/- 0.83 NG/DL/MN.
在19例无男性化表现的不明原因多毛症患者中，检查项目包括Δ4-雄烯二酮（A）、睾酮、硫酸脱氢表雄酮。A似乎是最佳的高雄激素血症参数。然而，该组中有5例患者所有这些激素的值均正常。促肾上腺皮质激素试验中17-羟孕酮反应异常提示存在轻度21-羟化酶缺乏所致的先天性肾上腺皮质增生。根据古塔伊方法，我们的Δ-OHP正常值为1.58±0.83纳克/分升/分钟。
