Hiraoka M, Adaniya H
J Electrocardiol. 1983 Apr;16(2):123-32. doi: 10.1016/s0022-0736(83)80016-8.
The function of the atrial preferential conduction routes was examined by the microelectrode technique under normal and abnormal conditions in excised rabbit hearts. The sinus impulse during normal conditions traveled faster along the left and the right branch of the crista terminalis (anterior and posterior preferential routes, respectively) in the atrium toward the A-V node. Cutting of either route caused a delay of the impulse arrival in the zone beyond the lesion. The internodal conduction time was delayed 12 msec upon cutting of the posterior route, but there was no conduction delay after cutting the anterior route. This indicates that the posterior path is the dominant conduction route under normal conditions. When both routes were cut, the internodal conduction time was delayed 33 msec from the control value. During abnormal conditions, an ectopic pacemaker was found to occur mainly in the regions of two routes, as well as in the coronary sinus region. The cutting of either route, combined with the application of acetylcholine or high external K+, resulted in easier provocation of re-entrant arrhythmias in response to premature-stimuli than before the cutting.
采用微电极技术，在正常和异常条件下，对离体兔心的心房优先传导途径的功能进行了研究。在正常情况下，窦房结冲动沿心房内终嵴的左、右分支（分别为前、后优先传导途径）更快地传向房室结。切断任何一条途径都会导致冲动到达病变部位以外区域的延迟。切断后传导途径时，结间传导时间延迟12毫秒，但切断前传导途径后无传导延迟。这表明在正常情况下后传导途径是主要的传导途径。当两条途径都被切断时，结间传导时间比对照值延迟33毫秒。在异常情况下，发现异位起搏点主要出现在两条传导途径区域以及冠状窦区域。切断任何一条途径，再加上应用乙酰胆碱或高浓度细胞外钾离子，与切断前相比，更容易因过早刺激而诱发折返性心律失常。
