Swanson D K, Myerowitz P D, Hasegawa B, Van Lysel M S, Watson K M, Frantz D W, Banaszak S, Hausman-Stokes E, Peppler W W, Dobbins J T
J Surg Res. 1983 Jun;34(6):524-32. doi: 10.1016/0022-4804(83)90105-1.
Standard angiography demonstrates the anatomy of arterial occlusive disease but does not define its physiological significance. However, measurement of flow in a compromised vessel at rest and following peripheral dilatation provides important physiological information. Using digital subtraction angiography, femoral arterial flows determined by the cross-correlation transit time technique were compared to measurements by electromagnetic flowmeter. Thirty-five femoral arterial flow measurements were obtained in nine dogs instrumented with an electromagnetic flow probe and balloon occluder. Renografin 76 (7 cc) was power-injected at 14 cc/sec into the distal abdominal aorta. Angiographic flow measurements correlated well with electromagnetic flowmeter measurements (r = 0.94, standard deviation of the difference (SDD) = 15 ml/min). Intravenous studies provided somewhat poorer correlation due to difficulties in defining dimensions (r = 0.72, SDD = 36). Paired contrast injections (2 injections in succession) in 11 studies increased flow from an average of 80 to 250 ml/min (a 210 +/- 100% increase), providing an estimate of a vessel's capacity to provide increased flow during peripheral dilatation. Thus, reliable angiographic flow determinations may be obtained by arterial and intravenous contrast injections, adding physiological information to anatomical definition.
标准血管造影可显示动脉闭塞性疾病的解剖结构，但无法确定其生理意义。然而，测量受损血管在静息状态下以及外周血管扩张后的血流量可提供重要的生理信息。利用数字减影血管造影术，将通过互相关渡越时间技术测定的股动脉血流量与用电磁流量计测量的结果进行比较。在9只装有电磁流量探头和球囊封堵器的狗身上进行了35次股动脉血流量测量。将76%泛影葡胺（7毫升）以14毫升/秒的速度注入腹主动脉远端。血管造影测量的血流量与电磁流量计测量结果相关性良好（r = 0.94，差值标准差（SDD）= 15毫升/分钟）。静脉注射研究的相关性稍差，原因是确定血管尺寸存在困难（r = 0.72，SDD = 36）。在11项研究中进行的成对造影剂注射（连续注射2次）使血流量从平均80毫升/分钟增加到250毫升/分钟（增加210±100%），从而估计了血管在外周血管扩张时增加血流量的能力。因此，通过动脉和静脉注射造影剂可获得可靠的血管造影血流量测定结果，为解剖学定义增添了生理信息。
