Prodromal acquired immune deficiency syndrome in Australian homosexual men.

The acquired immune deficiency syndrome (AIDS) was first reported in 1981 in homosexual men. Since then, it has shown an alarming increase in frequency. The syndrome has now been described in other population groups as well, in particular in persons with haemophilia who are exposed to frequent parenteral injections of blood or blood products, and in sexual contacts of those in at-risk groups. This report deals with two cases of this syndrome which occurred in homosexual men residing in Sydney. These cases are among the first reported in Australia, but, undoubtedly, many more will be forthcoming. Both patients have a profound defect in cellular immunity. The cause of this condition remains a mystery, although viral infection has been suggested. Therapeutic approaches have not yet been established. Clinicians and laboratory workers should be aware that this condition is now present in Australia, and should take appropriate precautions to avoid infection and to limit its spread.