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[退休铅作业工人的对照研究]

[Control studies on retired lead workers].

作者信息

Jahn O, Meisinger V

出版信息

Acta Med Austriaca. 1978;5(1):11-6.

PMID:685635
Abstract

Nine lead-workers, with an exposure time of 26 years, are investigated 10 years, after they had retired. There are no differences in the blood-count, hemoglobin, blood-lead level, urin-delta-aminolevulinic-acid, urincoproporphyrin and delta-aminolevulinic-acid-dehydratase-activity in their blood, upon comparison with a control group without lead-exposure. The mean urinary excretion of lead (0.119 mumol/g Kreatinin = 24 microgram/g Kr.) was 8 times higher than of reached by the controls (0.014 mumol/g Kr. = 2.7 microgram/g Kr.). The injection of CaNa2-EDTA increased the lead excretion to 0.197 mumol/g Kr. = 40.8 microgram/g Kr., in the control group 0.123 mumol/g Kr. - 25.7 microgram/g Kr. (62%). Therefore these two investigations are recommended for detection of previous lead exposure.

摘要

对9名铅作业工人进行了调查,他们的接触时间为26年,退休10年后接受调查。与无铅接触的对照组相比,他们血液中的血细胞计数、血红蛋白、血铅水平、尿δ-氨基乙酰丙酸、尿粪卟啉和δ-氨基乙酰丙酸脱水酶活性均无差异。铅的平均尿排泄量(0.119微摩尔/克肌酐=24微克/克肌酐)比对照组(0.014微摩尔/克肌酐=2.7微克/克肌酐)高8倍。注射CaNa2-EDTA后,铅排泄量增加到0.197微摩尔/克肌酐=40.8微克/克肌酐,对照组为0.123微摩尔/克肌酐-25.7微克/克肌酐(62%)。因此,建议进行这两项检查以检测既往铅接触情况。

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