Andreeva M Kh, Bozadzhieva E K, Platonova E S, Zografski S G, Mendizov I Kh
Probl Endokrinol (Mosk). 1983 Mar-Apr;29(2):39-44.
The effectiveness of high doses of reserpine was studied in two groups of patients, suffering from Icenko-Cushing's disease. The patients of the first group received gamma-beam therapy combined with high doses of reserpine. The patients of the second group were treated with gamma-beam radiation associated with unilateral adrenalectomy plus high doses of reserpine. The controls were treated as described above, but without reserpine use. The results obtained have shown that reserpine monotherapy is not recommended in Icenko-Cushing's disease. High doses of reserpine combined with gamma-beam radiation alone or coupled with unilateral adrenalectomy shortened the period of the appearance of remission. The arterial blood pressure was significantly lower in patients treated with high doses of reserpine.
在两组患有伊琴科 - 库欣病的患者中研究了高剂量利血平的疗效。第一组患者接受了伽马射线治疗并联合高剂量利血平。第二组患者接受了伽马射线辐射联合单侧肾上腺切除术并加用高剂量利血平。对照组按上述方法治疗，但未使用利血平。所获得的结果表明，不建议在伊琴科 - 库欣病中使用利血平单一疗法。高剂量利血平单独与伽马射线辐射联合或与单侧肾上腺切除术联合使用可缩短缓解出现的时间。接受高剂量利血平治疗的患者动脉血压明显较低。
