Koga H, Mori K, Kawano T, Tsutsumi K, Jinnouchi T
Surg Neurol. 1983 Jun;19(6):548-53. doi: 10.1016/0090-3019(83)90381-6.
A 65-year-old woman appeared with a progressive dementia, gait disturbance, and Parinaud's syndrome. A computed tomography scan, an angiogram of the vertebral artery, and metrizamide ventriculography demonstrated a marked hydrocephalus. A giant aneurysm at the termination of the basilar artery projected into the third ventricle producing partial obstruction of the aqueduct. The symptoms were resolved by a ventriculoperitoneal shunt; but after a month, the patient again showed the upward-gaze palsies concomitant with occurrence of shunt malfunction. The possible mechanisms of Parinaud's syndrome observed in the patient are discussed.
一名65岁女性出现进行性痴呆、步态障碍和帕里诺综合征。计算机断层扫描、椎动脉血管造影和甲泛葡胺脑室造影显示明显脑积水。基底动脉末端的巨大动脉瘤突入第三脑室,导致导水管部分梗阻。脑室腹腔分流术使症状得到缓解;但一个月后,患者再次出现向上凝视麻痹,同时伴有分流装置故障。文中讨论了该患者出现帕里诺综合征的可能机制。