Palmaz J C, Carson S N, Hunter G, Weinshelbaum A
Surgery. 1983 Jul;94(1):91-4.
Hypoplasia of the abdominal aorta distal to the origin of the renal arteries may be a contributing factor in the development of early atherosclerosis. The abnormal aortic configuration and resultant increased stress forces may account for the localization of the disease to the aortoiliac segment. The increased frequency of single bifurcating lumbar arteries at the L4-L5 level, easily demonstrable on conventional arteriograms, suggests that the aortic hypoplasia may result from excessive fusion of the paired dorsal aortas during embryonic life. Hypoplasia of the infrarenal aorta is present in 9% of females with aortoiliac disease, and it is believed to be uncommon in males. A review of 408 peripheral arteriograms of males revealed 18 cases (4.4%) of hypoplasia of the abdominal aorta. Males with hypoplastic aortas develop symptoms 10 years earlier than those with normal-sized aortas and 10 years later than females with similar narrowing of the distal aorta.
肾动脉起源远端的腹主动脉发育不全可能是早期动脉粥样硬化发展的一个促成因素。主动脉的异常形态以及由此产生的应力增加可能是该疾病定位于主-髂动脉段的原因。在L4-L5水平单支分叉腰动脉的频率增加，在传统动脉造影中很容易显示，这表明主动脉发育不全可能是由于胚胎期成对的背主动脉过度融合所致。在患有主-髂动脉疾病的女性中，9%存在肾下腹主动脉发育不全，据信在男性中并不常见。对408例男性外周动脉造影的回顾显示，有18例（4.4%）腹主动脉发育不全。主动脉发育不全的男性出现症状的时间比主动脉正常大小的男性早10年，比远端主动脉有类似狭窄的女性晚10年。
