Dancot H, Jortay A, Feremans W
Acta Chir Belg. 1983 Mar-Apr;83(2):114-23.
Eighty-two patients with a head and neck extranodal lymphoma were treated and followed up by the same medical team during the period 1952-1981. Most of these tumors, which frequently originated from the Waldeyer ring, evolved by nodal infiltration, first in the neck and later in the abdomen. Association of a GI tract lymphomatous process with a head and neck lymphoma is of particular interest specially regarding gastric localizations (7/82). The treatment of choice is irradiation which is able to control initial head and neck disease, but local recurrences are frequent and represent 25% of the cases. Considering 5 year survivals, it is 49% on the whole series, 57% for the 31 stage I, 41.5% for the 21 stage II; only one patient over the five stage III and IV survived 5 years. For patients with lymphoma of diffuse type, adjuvant polychemotherapy should be considered at the start of management.
1952年至1981年期间，同一医疗团队对82例头颈部结外淋巴瘤患者进行了治疗和随访。这些肿瘤大多起源于瓦尔代尔环，通过淋巴结浸润发展，首先累及颈部，随后累及腹部。胃肠道淋巴瘤与头颈部淋巴瘤的关联，尤其是胃部淋巴瘤（82例中有7例），特别值得关注。首选治疗方法是放疗，放疗能够控制头颈部的初始疾病，但局部复发很常见，占病例的25%。考虑到5年生存率，整个系列为49%，31例I期患者为57%，21例II期患者为41.5%；五例III期和IV期患者中只有一例存活了5年。对于弥漫型淋巴瘤患者，在治疗开始时应考虑辅助多药化疗。
