Hjortrup A, Kehlet H, Lockwood K, Hasner E
Acta Obstet Gynecol Scand. 1983;62(1):55-7. doi: 10.3109/00016348309155759.
Twenty-nine consecutive patients with polycystic ovary (PCO) syndrome (defined as hirsutism plus oligomenorrhea or secondary amenorrhea, and excluding Cushing's syndrome, an androgen-secreting adrenal or ovarian tumor or adrenocortical hyperplasia) were treated with ovarian wedge resection leaving normal-sized ovaries. Long-term follow-up from 2.3-9.5 years (mean 5.7 years) showed that 26 of 29 patients (90%) had established normal menstrual cycles. Fertility and normal pregnancies were achieved in all 10 patients (100%) with normal postoperative menstrual cycles who desired to conceive, but not in the 3 patients with remaining postoperative oligomenorrhea. Eight of 9 patients who were obese preoperatively and who had normal postoperative menstrual cycles showed a major weight loss after wedge resection. In contrast, none of the preoperatively obese patients, who remained oligomenorrheic after surgery, lost weight. Hirsutism was not cured by wedge resection. It is concluded that ovarian wedge resection should still be considered useful in patients with PCO.
29例连续的多囊卵巢（PCO）综合征患者（定义为多毛症加月经过少或继发性闭经，排除库欣综合征、分泌雄激素的肾上腺或卵巢肿瘤或肾上腺皮质增生）接受了卵巢楔形切除术，保留卵巢大小正常。2.3至9.5年（平均5.7年）的长期随访显示，29例患者中有26例（90%）建立了正常月经周期。所有10例术后月经周期正常且希望怀孕的患者（100%）实现了生育和正常妊娠，但3例术后仍有月经过少的患者未怀孕。9例术前肥胖且术后月经周期正常的患者中有8例在楔形切除术后体重显著减轻。相比之下，术后仍有月经过少的术前肥胖患者无一例体重减轻。楔形切除术未能治愈多毛症。结论是，卵巢楔形切除术对PCO患者仍应被认为是有用的。
