Sugihara S, Yamaguchi A, Matsumura K, Fujimura H
Am J Gastroenterol. 1983 Jun;78(6):341-5.
This paper describes a unique case of combined malignant lymphoma of the jejunum and multiple synchronous carcinomas of colon and rectum. The jejunal tumor developed obstructive growth without regional lymph node involvement. Histologically, it was a malignant lymphoma corresponding to medium-sized cell type of follicular lymphoma, suggesting B cell origin in the bowel wall. In the colon and rectum, except for the transverse segment, there were three encircling, annular infiltrative tumors, and six polyps with malignant change. They developed independently, separated by an intact mucosa suggesting multiple synchronous cancers. Histologically they showed adenocarcinoma with or without mucus production, adenosquamous cell carcinoma, and villotubular adenocarcinoma. A case report is presented with a brief review of the incidence and pathogenesis of both jejunal and colonic tumors.
本文描述了一例空肠恶性淋巴瘤合并结肠和直肠多发同步癌的独特病例。空肠肿瘤呈阻塞性生长，无区域淋巴结受累。组织学上，它是一种对应于滤泡性淋巴瘤中型细胞类型的恶性淋巴瘤，提示起源于肠壁的B细胞。在结肠和直肠，除横段外，有三个环绕的、环形浸润性肿瘤，以及六个发生恶变的息肉。它们独立发生，被完整的黏膜分隔开，提示为多发同步癌。组织学上，它们表现为腺癌，有或无黏液分泌、腺鳞癌和绒毛管状腺癌。现报告一例病例，并对空肠和结肠肿瘤的发病率及发病机制进行简要综述。
