Regan P T, Phillips S F, Dimagno E P
Am J Dig Dis. 1978 Aug;23(8):759-62. doi: 10.1007/BF01072367.
A patient with exocrine pancreatic insufficiency and hypoalbuminemic edema was shown also to have a protein-losing gastropathy secondary to giant hypertrophic gastritis (Ménétrier's disease). Despite continuation of excessive gastric protein loss, the manifestations of hypoproteinemia were reversed by oral pancreatic enzyme replacement therapy. We speculate that impaired intraluminal proteolysis exaggerated the consequences of gastric protein loss.
一名患有外分泌性胰腺功能不全和低蛋白血症性水肿的患者还被发现患有继发于巨大肥厚性胃炎（梅内特里尔病）的蛋白丢失性胃病。尽管持续存在大量胃蛋白丢失，但口服胰酶替代疗法使低蛋白血症的表现得到了逆转。我们推测管腔内蛋白水解受损加剧了胃蛋白丢失的后果。
