Dreiling D A, Nacchiero M
Am J Gastroenterol. 1978 Apr;69(4):491-3.
The acute administration of Imuran and hydrocortisone significantly decrease pancreatic flow and protein output in canines. This observed phenomenon may explain the gastrointestinal side reactions encountered in clinical usage of these potent immunosuppresants.
急性给予硫唑嘌呤和氢化可的松可显著降低犬的胰腺血流量和蛋白质输出量。这一观察到的现象可能解释了这些强效免疫抑制剂在临床使用中所遇到的胃肠道副作用。