Gomes A S, Busuttil R W, Baker J D, Oppenheim W, Machleder H I, Moore W S
Arch Surg. 1983 Jul;118(7):817-25. doi: 10.1001/archsurg.1983.01390070029007.
We treated 11 patients with congenital arteriovenous malformations (AVMs) with staged transcatheter arterial embolization of their lesions. In nine patients, the AVM involved an extremity. One patient had multiple pulmonary AVMs, another an AVM of the pancreas. Embolization was performed using polyvinyl alcohol sponge (Ivalon) particles and Gianturco-Wallace colls. Nine patients had a systemic response to embolization, characterized by pain, fever, leukocytosis, and elevated enzyme levels. Complications (three major, two minor) developed in five patients. A total of 28 staged embolizations were performed, with follow-up to 36 months. We found transcatheter embolization a useful palliative therapy in treating congenital AVMs. It should be considered as a therapeutic alternative for patients with unresectable AVMs, those for whom amputation would be required, and those who are otherwise poor surgical candidates.
我们对11例先天性动静脉畸形（AVM）患者的病变进行了分期经导管动脉栓塞治疗。9例患者的AVM累及一个肢体。1例患者有多发肺AVM，另1例患者有胰腺AVM。栓塞治疗使用聚乙烯醇海绵（Ivalon）颗粒和Gianturco-Wallace线圈。9例患者对栓塞治疗有全身反应，表现为疼痛、发热、白细胞增多和酶水平升高。5例患者出现并发症（3例严重，2例轻微）。共进行了28次分期栓塞治疗，随访至36个月。我们发现经导管栓塞治疗是治疗先天性AVM的一种有效的姑息治疗方法。对于无法切除AVM的患者、需要截肢的患者以及其他手术条件较差的患者，应将其视为一种治疗选择。
