Chideckel E W, Edwards D
Biochem J. 1983 Feb 15;210(2):617-9. doi: 10.1042/bj2100617.
The non-metabolizable amino acids alpha-aminoisobutyric acid (AIB) and cycloleucine and the poorly metabolizable amino acid D-alanine potently stimulated hepatic ornithine decarboxylase (ODC) activity in starved rats. The stimulation by AIB was shown to have several of the characteristics of stimulation by a protein meal and occurred in hypophysectomized animals. AIB also stimulated renal, but not brain or heart, ODC activity.
不可代谢的氨基酸α-氨基异丁酸(AIB)、环亮氨酸以及代谢能力较差的氨基酸D-丙氨酸,能有效刺激饥饿大鼠肝脏中的鸟氨酸脱羧酶(ODC)活性。研究表明,AIB引起的刺激具有蛋白质餐刺激的若干特征,且在垂体切除的动物中也会出现。AIB还能刺激肾脏的ODC活性,但对大脑或心脏的ODC活性无刺激作用。