De Bortoli M, Fumero S, Mondino A
Boll Soc Ital Biol Sper. 1983 Jan 31;59(2):226-32.
A method for determining cAMP-binding activity in human mammary tumor cytosol is described and the results of routine assay on 57 tumor samples are presented in relation to the estrogen and progesterone receptor levels. Results show that the values of each single parameter are very largely dispersed. The estrogen receptor/cAMP-binding protein ratio distributes in a very interesting way, in view of a retrospective clinical trial now in progress.
本文描述了一种测定人乳腺肿瘤胞质溶胶中cAMP结合活性的方法,并给出了57个肿瘤样本的常规检测结果与雌激素和孕激素受体水平的关系。结果表明,每个单一参数的值分布极为分散。鉴于目前正在进行的一项回顾性临床试验,雌激素受体/cAMP结合蛋白的比值分布方式非常有趣。