The effect of leukotrienes C4 and D4 on microcirculatory flow in humans.
作者信息
Bisgaard H, Kristensen J, Sondergaard J
出版信息
Br J Dermatol. 1983 Jul;109 Suppl 25:124-5. doi: 10.1111/j.1365-2133.1983.tb06822.x.
Abstract
By quantifying the flare response, leukotrienes LTC4 and LTD4 were shown to increase the microcirculatory flow in a sigmoidal dose-response relation over the dose-range of 6.25-800 pmol. LTD4 was found to be more potent than LTC4 after 5 min, but not after 15 min, as estimated by this method. Laser-Doppler flowmeter studies confirmed that LTD4 is a more potent vasodilator than LTC4.
摘要
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