Eley B M, Garrett J R
Biomaterials. 1983 Apr;4(2):73-80. doi: 10.1016/0142-9612(83)90043-1.
Soft tissue degradation of the 3 principal amalgam phases have been investigated in relation to their role in the formation of the amalgam tattoo. Each phase, finely powdered, was implanted subcutaneously into the submandibular region of guinea-pigs for periods ranging from 1 week to 1 year. The rates of breakdown were assessed radiographically and the final lesions were examined by light and electron microscopy and X-ray microanalysis. gamma 2 (Sn7Hg) phase degraded rapidly, mainly extracellularly, and did not produce a tattoo. Both mercury and tin disappeared from the lesion. gamma 1 (Ag2Hg3) phase degraded less rapidly, both extra and intracellularly, and produced a small tattoo. Mercury was lost from the lesion. gamma (Ag3Sn) phase degraded slowly, intracellularly, and produced a large tattoo. Tattoos always resulted from persistence of minute particles of silver and sulphur associated with basal lamina and connective tissue.
已对三种主要汞合金相的软组织降解情况进行了研究，探讨了它们在汞合金纹身形成过程中的作用。将每种细粉状的相皮下植入豚鼠的下颌下区域，植入时间从1周至1年不等。通过放射照相评估分解速率，并通过光学显微镜、电子显微镜和X射线微分析检查最终病变。γ2（Sn7Hg）相迅速降解，主要在细胞外降解，未产生纹身。汞和锡均从病变处消失。γ1（Ag2Hg3）相降解速度较慢，在细胞外和细胞内均有降解，并产生小的纹身。汞从病变处流失。γ（Ag3Sn）相在细胞内缓慢降解，并产生大的纹身。纹身总是由与基底层和结缔组织相关的微小银和硫颗粒的存留导致的。
