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腋股及股股移植物:6年经验,重点关注术中血流测量与移植物存活的关系。

Axillofemoral and femorofemoral grafts: a 6-year experience with emphasis on the relationship of peroperative flow measurement to graft survival.

作者信息

Graham J C, Cameron A E, Ismail H I, Hamilton W A, Law Y F, Roberts V C, Cotton L T

出版信息

Br J Surg. 1983 Jun;70(6):326-31. doi: 10.1002/bjs.1800700607.

Abstract

Over a 6-year period 64 axillofemoral bypass and femorofemoral crossover grafts have been performed in 58 patients, most of whom were considered unfit for intra-abdominal surgery. Indications were peripheral ischaemia in 78 per cent and disabling claudication in 22 per cent. The limb salvage rate at 3 years was 75 per cent. No claudicants lost limbs, but only one-third of patients presenting with forefoot gangrene or ulceration avoided amputation. Most patients presenting with ischaemic symptoms at rest had associated femoropopliteal and distal disease, confirmed by the ankle pressure index measurements, and this influenced graft patency. Although the cumulative patency at 3 years for all grafts combined was 57 per cent with similar patencies for both the axillofemoral and femorofemoral grafts, early occlusion was more common in axillofemoral grafts and this may be reduced in bifemoral grafts by the increased flow rate in the vertical limbs. Peroperative electromagnetic flowmeter measurements were made after reconstruction on 55 femoral arteries in 46 of the patients and graft flow velocities were derived from these measurements. Comparison between velocities from those grafts remaining patent and those subsequently occluding showed a high incidence of occlusion in grafts with a maximal velocity after distal vasodilatation of less than 8 cm/s. Graft occlusion after the first postoperative month was more commonly associated with other factors such as continued smoking, severity of distal disease and perigraft infection.

摘要

在6年期间,对58例患者施行了64例腋股动脉搭桥术和股股交叉移植术,其中大多数患者被认为不适合进行腹部手术。适应症为78%的患者存在周围缺血,22%的患者有致残性跛行。3年时的肢体挽救率为75%。跛行患者无一例肢体丧失,但仅有三分之一表现为前足坏疽或溃疡的患者避免了截肢。大多数静息时出现缺血症状的患者伴有股腘动脉及远端病变,经踝压指数测量得以证实,这影响了移植血管的通畅率。尽管所有移植血管3年时的累积通畅率为57%,腋股动脉和股股动脉移植血管的通畅率相似,但腋股动脉移植血管早期闭塞更为常见,而在双股动脉移植中,垂直肢体血流速度增加可能会降低这种情况的发生。对46例患者的55条股动脉重建术后进行了术中电磁流量计测量,并根据这些测量得出移植血管的流速。对仍保持通畅的移植血管和随后闭塞的移植血管的流速进行比较,结果显示,远端血管扩张后最大流速小于8 cm/s的移植血管闭塞发生率较高。术后第一个月后移植血管闭塞更常与其他因素有关,如持续吸烟、远端病变的严重程度和移植血管周围感染。

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