Summers B, Cypess R H, Dolinsky Z S, Burright R G, Donovick P J
Brain Res Bull. 1983 Apr;10(4):547-50. doi: 10.1016/0361-9230(83)90153-3.
Binghamton Heterogeneous stock mice intubated with embryonated eggs from the common parasite of dogs, Toxocara canis, display dramatic alterations in behavior. Many of these behavioral changes are markedly attenuated if mice are maintained also on a drinking solution containing lead acetate. The data presented here, however, show that the extensive neural degeneration of the CNS occurs after T. canis infection and that the nature and extent of this degeneration is similar, regardless of whether mice had been administered parasites alone or in combination with lead. Thus the neuropathological data reported in detail here cannot account for the striking interactive influence of T. canis and lead on behavior.
用犬弓首蛔虫（狗的常见寄生虫）的感染性虫卵对宾厄姆顿异种品系小鼠进行插管后，小鼠的行为会出现显著变化。如果小鼠同时饮用含有醋酸铅的溶液，许多这些行为变化会明显减弱。然而，此处呈现的数据表明，犬弓首蛔虫感染后中枢神经系统会发生广泛的神经退化，并且这种退化的性质和程度是相似的，无论小鼠是单独感染寄生虫还是同时感染寄生虫与铅。因此，此处详细报道的神经病理学数据无法解释犬弓首蛔虫和铅对行为的显著交互影响。
