Lahav M, Gutman I
Am J Ophthalmol. 1978 Aug;86(2):239-44. doi: 10.1016/s0002-9394(14)76819-9.
On examining 54 globes that harbored choroidal malignant melanomas, we found 28 tumors to be composed of spindle cells; 24, of mixed cells; and two, of epitheloid cells. In 80% of the tumors studied, pigment-laden cells had accumulated away from the tumor region and at the periphery of the subretinal space. The number of cells increased in proportion to the extent of retinal detachment, a finding that related directly to the size of the tumor.
在检查54个患有脉络膜恶性黑色素瘤的眼球时,我们发现28个肿瘤由梭形细胞组成;24个由混合细胞组成;2个由上皮样细胞组成。在80%的研究肿瘤中,含色素细胞在远离肿瘤区域且位于视网膜下间隙周边处积聚。细胞数量与视网膜脱离程度成比例增加,这一发现与肿瘤大小直接相关。