Hasegawa I, Kuriki S, Matsuno S, Matsumoto G
Clin Orthop Relat Res. 1983 Jul-Aug(177):283-8.
A new system for measuring the resistivity of articular cartilage is based on the four-point probe technique. The system measures resistivity as a function of depth from the articular surface. The measurements obtained showed that the conductivity, kappa, of articular cartilage equilibrated in Ringer's solution (pH, 7.4) is constant in all zones, with a value of 6-10 X 10(-3) mho/cm. Conversely, kappa of articular cartilage equilibrated in distilled water varies distinctly, being low in the superficial zone (about 0.7 X 10(-3) mho/cm) and high in the middle to deep zone (about 3 X 10(-3) mho/cm). This is almost the same variation shown by the fixed charge density, FCD, which was measured by the tracer cation method; a linear correlation between kappa and the FCD was found (correlation coefficient, 0.88). These observations were well understood based on the Donnan equilibrium; the mobility of Na+ in cartilage was thought to be independent of FCD.
一种用于测量关节软骨电阻率的新系统基于四点探针技术。该系统测量电阻率随距关节表面深度的变化。所获得的测量结果表明，在林格氏溶液（pH值为7.4）中平衡的关节软骨的电导率κ在所有区域都是恒定的，其值为6 - 10×10⁻³姆欧/厘米。相反，在蒸馏水中平衡的关节软骨的κ变化明显，在表层区域较低（约0.7×10⁻³姆欧/厘米），在中深层区域较高（约3×10⁻³姆欧/厘米）。这与通过示踪阳离子法测量的固定电荷密度FCD所显示的变化几乎相同；发现κ与FCD之间存在线性相关性（相关系数为0.88）。基于唐南平衡，这些观察结果很容易理解；软骨中Na⁺的迁移率被认为与FCD无关。
