甜橙外果皮的光毒性和接触毒性反应：唇炎的常见病因？
Phototoxic and contact toxic reactions of the exocarp of sweet oranges: a common cause of cheilitis?
作者信息
Volden G, Krokan H, Kavli G, Midelfart K
出版信息
Contact Dermatitis. 1983 May;9(3):201-4. doi: 10.1111/j.1600-0536.1983.tb04358.x.
Irritant skin reactions were produced within 1 h after application of the exocarp of sweet oranges or alcoholic extracts therefrom. Such reactions faded within 48 h. The exocarp, or extracts thereof, induced phototoxic reactions which were strongest at 72 h after exposure. The phototoxic reactions were only induced in natural blondes and only with some oranges. The in vivo phototoxic reactions were confirmed in vitro, causing a slight but clear photo-inhibition of Candida albicans. Only some oranges inhibited growth.
甜橙外果皮或其酒精提取物涂抹后1小时内会产生刺激性皮肤反应。此类反应在48小时内消退。外果皮或其提取物会引发光毒性反应，在暴露后72小时时最强。光毒性反应仅在天生的金发人群中出现，且只在某些橙子中引发。体内光毒性反应在体外得到证实，对白色念珠菌产生轻微但明显的光抑制作用。只有部分橙子会抑制其生长。
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