Roos P H, Kolb-Bachofen V, Schlepper-Schäfer J, Monsigny M, Stockert R J, Kolb H
FEBS Lett. 1983 Jul 4;157(2):253-6. doi: 10.1016/0014-5793(83)80556-0.
In the rat liver both hepatocytes and macrophages have been shown to express on the surface lectins with similar binding specificity for galactose residues. Functionally the two lectins differ in the uptake of ligands. Whereas the hepatocytes ingest molecules and small particles (less than 10 nm), the macrophages take up particles only. Antisera raised against hepatic galactose-specific receptor failed to react with the macrophage lectin but blocked ligand binding to the hepatocyte only, indicating either a different antigenic structure or membrane localization of the two lectins.
在大鼠肝脏中，已证明肝细胞和巨噬细胞表面均表达对半乳糖残基具有相似结合特异性的凝集素。在功能上，这两种凝集素在配体摄取方面存在差异。肝细胞摄取分子和小颗粒（小于10纳米），而巨噬细胞仅摄取颗粒。针对肝脏半乳糖特异性受体产生的抗血清与巨噬细胞凝集素不发生反应，但仅阻断配体与肝细胞的结合，这表明两种凝集素的抗原结构或膜定位不同。
