Ibraimov A I
Hum Genet. 1983;63(4):384-91. doi: 10.1007/BF00274767.
The distribution of chromosomal Q-polymorphic bands was studied in different human populations. The populations studied showed no differences in the relative amount of Q bands in all the 12 polymorphic loci of seven autosomes, but interpopulation differences did exist in the absolute amount of Q bands in all the 12 potentially polymorphic loci of seven autosomes, these differences consisting of uniform increases or decreases in this absolute amount. Comparisons of the mean number of Q-heterochromatin bands with fluorescence levels 4 and 5 per individual showed a consistent prevalence of this quantitative parameter of chromosomal Q polymorphism in females as compared to males in all the national groups. It is suggested that there is some dosage compensation of chromosomal Q-heterochromatin material in females due to the absence of a chromosome in their genome, which is able to "compensate" for the large Q band in chromosome Y which is present only in the karyotype of males.
在不同人群中研究了染色体Q多态带的分布情况。所研究的人群在七条常染色体的所有12个多态位点上，Q带的相对量没有差异，但在七条常染色体的所有12个潜在多态位点上，Q带的绝对量存在人群间差异，这些差异表现为该绝对量的一致增加或减少。将每个个体荧光水平为4和5的Q-异染色质带的平均数量进行比较，结果显示，在所有民族群体中，女性染色体Q多态性的这一数量参数比男性更为普遍。有人提出，由于女性基因组中缺少一条染色体，而这条染色体能够“补偿”仅存在于男性核型中的Y染色体上的大Q带，因此女性染色体Q-异染色质物质存在某种剂量补偿。
