Ibraimov A I, Karagulova G O, Kim E Y
Laboratory of Human Genetics, National Center of Cardiology and Internal Medicine, Kyrghyzstan, C.I.S.
Cytobios. 2000;102(399):35-53.
The relationship between the basic quantitative characteristics of the Q-heterochromatin (Q-HR) region variability of autosomes and of the Y chromosome in human populations was examined. A definite relationship between the mean number of Q-HR per individual, the distribution and frequencies of Q-HR on autosomes and the size of the Q-heterochromatin segment of the Y chromosome at the population level was shown to exist. The amount of autosomal Q-HR was lower in individuals with larger Q-heterochromatin segments on Y chromosomes, and vice versa. The hypothesis that the amount of chromosomal Q-HR in the genome of modern human populations may be under the control of natural selection, is discussed.
研究了人类群体中常染色体和Y染色体Q-异染色质（Q-HR）区域变异性的基本定量特征之间的关系。结果表明，在群体水平上，个体的Q-HR平均数量、常染色体上Q-HR的分布和频率与Y染色体Q-异染色质片段大小之间存在明确的关系。Y染色体上具有较大Q-异染色质片段的个体，其常染色体Q-HR的数量较少，反之亦然。文中还讨论了现代人类群体基因组中染色体Q-HR数量可能受自然选择控制的假说。
