Bienzle U, Komp H, Feldheim M, Reimer A, Steffen E, Guggenmoos-Holzmann I
Hum Genet. 1983;63(4):400-3. doi: 10.1007/BF00274769.
In a population survey in Liberia, West Africa, 12 major tribes were examined for the prevalence of Hb S, Hb C, and the beta thalassaemia (beta Thal) gene. Hb C is rare; Hb S and beta Thal occur in polymorphic frequencies. The distribution of both genes shows an inverse correlation. The beta Thal trait was diagnosed by quantitation of Hb A2 on DE 52-microchromatography. This method proved to be reliable and useful for mass screening.
在西非利比里亚的一项人口调查中，对12个主要部落进行了血红蛋白S（Hb S）、血红蛋白C（Hb C）和β地中海贫血（β Thal）基因流行情况的检测。Hb C较为罕见；Hb S和β Thal以多态频率出现。两种基因的分布呈负相关。通过DE 52微柱层析法对Hb A2进行定量来诊断β Thal性状。该方法被证明对于大规模筛查可靠且有用。
