Bandmann H J, Kaess H, Langer H D
Hautarzt. 1983 May;34(5):217-20.
A patient reported that she developed various shock-like symptoms upon intake of alcohol, acetylsalicylic acid, or after injection of contrast medium. After provocation with alcohol applied orally and following endoscopy flush, tachycardia, and a severe headache followed immediately by painful diarrhea were observed. According to our diagnosis the patient had urticaria pigmentosa involving the bone marrow and an enlarged liver and spleen, respectively. The suspected intestinal mastocytosis was confirmed histologically by a biopsy from the jejunum. It was concluded that the symptoms were the result of a direct activation of the accumulated intestinal mast cells. The differential diagnosis of mastocytosis as opposed to allergic gastroenteritis, sprue, and carcinoid is discussed.
一名患者报告称，她在摄入酒精、乙酰水杨酸后，或注射造影剂后出现了各种类似休克的症状。口服酒精激发试验后，在内镜冲洗后，立即观察到心动过速、严重头痛，随后出现疼痛性腹泻。根据我们的诊断，该患者患有累及骨髓的色素性荨麻疹，肝脏和脾脏分别肿大。通过空肠活检组织学证实了疑似肠道肥大细胞增多症。得出的结论是，这些症状是肠道中积聚的肥大细胞直接激活的结果。讨论了肥大细胞增多症与过敏性肠胃炎、口炎性腹泻和类癌的鉴别诊断。
