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牛实验性感染间日锥虫时的白细胞反应

Leukocyte response in experimental Trypanosoma vivax infection in cattle.

作者信息

Esievo K A, Saror D I

出版信息

J Comp Pathol. 1983 Apr;93(2):165-9. doi: 10.1016/0021-9975(83)90002-6.

DOI:10.1016/0021-9975(83)90002-6
PMID:6863606
Abstract

Eight Zebu cattle were infected with Trypanosoma vivax stock Y58, while 8 served as uninfected controls. The infected animals developed early leukopenia due to concomitant lymphopenia and neutropenia. It is suggested that an increase in trypanosomal antigens and neuraminidase in the infected cattle at this time may have an effect on peripheral leukocytes.

摘要

8头瘤牛感染了活泼锥虫Y58株,另有8头作为未感染对照。由于同时出现淋巴细胞减少和中性粒细胞减少,感染的动物出现早期白细胞减少。有人认为,此时感染牛体内锥虫抗原和神经氨酸酶的增加可能对外周白细胞有影响。

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引用本文的文献

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To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host.从皮肤到全身:非洲锥虫进入和离开脊椎动物宿主时的免疫反应。
Front Immunol. 2020 Jun 12;11:1250. doi: 10.3389/fimmu.2020.01250. eCollection 2020.
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Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.布氏锥虫利用自然杀伤细胞杀死脾脏B2 B细胞。
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Trypanosoma vivax Adhesion to Red Blood Cells in Experimentally Infected Sheep.
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Patholog Res Int. 2016;2016:4503214. doi: 10.1155/2016/4503214. Epub 2016 May 16.
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A non-cytosolic protein of Trypanosoma evansi induces CD45-dependent lymphocyte death.伊氏锥虫的一种非胞质蛋白可诱导依赖CD45的淋巴细胞死亡。
PLoS One. 2009 May 29;4(5):e5728. doi: 10.1371/journal.pone.0005728.
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Host-parasite interactions in trypanosomiasis: on the way to an antidisease strategy.锥虫病中的宿主-寄生虫相互作用:通向抗疾病策略之路
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