Troyer C, Grossman M E, Silvers D N
J Am Acad Dermatol. 1983 May;8(5):724-8. doi: 10.1016/s0190-9622(83)70088-5.
Skin biopsy of a 10-year-old boy with a 3-week history of recurrent rash and fever demonstrated histologic changes suggesting a diagnosis of erythema marginatum associated with rheumatic fever. Subsequently, the patient developed classic cardiac and arthritic manifestations. Skin biopsy is recommended for the early diagnosis of rheumatic fever.
一名患有反复皮疹和发热3周病史的10岁男孩的皮肤活检显示出组织学变化，提示诊断为与风湿热相关的边缘性红斑。随后，该患者出现了典型的心脏和关节表现。建议进行皮肤活检以早期诊断风湿热。
