Quinn W B, Graebner J E, Arenson D J
J Foot Surg. 1983 Summer;22(2):178-82.
The use of various radioactive compounds in the diagnosis of osteomyelitis has been the topic of discussion by numerous authors. A great number of bone imaging agents have been experimented with and clinically applied with varying results. It is the intention of this article to detail and compare the use of two such agents: technetium-99m phosphonate, a phosphorus compound radioactively labeled with an isotope of technetium, and gallium citrate 67, a radioactive isotope of gallium. Both of these materials have specific indications and limitations. However, used in the proper setting, either singularly or in conjunction, they give the clinician precise information about pathologic processes. It is the clinician's careful interpretation of both positive and negative test results that enables him to make proper diagnosis and thus institute appropriate therapy.
多种放射性化合物在骨髓炎诊断中的应用一直是众多作者讨论的话题。大量的骨显像剂已经进行了试验并临床应用,结果各异。本文旨在详细介绍并比较两种此类显像剂的应用:锝-99m膦酸盐,一种用锝的同位素进行放射性标记的磷化合物,以及枸橼酸镓67,一种镓的放射性同位素。这两种物质都有特定的适应证和局限性。然而,在适当的情况下单独或联合使用,它们能为临床医生提供有关病理过程的精确信息。正是临床医生对阳性和阴性检查结果的仔细解读,使他能够做出正确的诊断并因此制定适当的治疗方案。